Iqcn^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Iqcn^em1Cya
• Name: IQ motif containing N; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7413046
• Gene: Iqcn Location: Chr8:71156106-71170299 bp, + strand Genetic Position: Chr8, 34.15 cM
• Alliance: Iqcn^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exons 3 and 4. (J:332231)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Iqcn Mutation: 24 strains or lines available

References

• Original: J:332231 Dai J, et al., IQCN disruption causes fertilization failure and male infertility due to manchette assembly defect. EMBO Mol Med. 2022 Dec 7;14(12):e16501
• All: 2 reference(s)