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Iqubem2Mngx
Endonuclease-mediated Allele Detail
Summary
Symbol: Iqubem2Mngx
Name: IQ motif and ubiquitin domain containing; endonuclease-mediated mutation 2, Mingxi Liu
MGI ID: MGI:7413079
Synonyms: IqubdeltaUB
Gene: Iqub  Location: Chr6:24444864-24515066 bp, - strand  Genetic Position: Chr6, 11.28 cM
Alliance: Iqubem2Mngx page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Not Applicable)
Mutation:    Intragenic deletion
    CRISPR-targeting deleted exons 3 and 4 deleted the Ubiquitin-like domain. (J:332237)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Iqub Mutation:  45 strains or lines available
References
Original:  J:332237 Zhang X, et al., Differential requirements of IQUB for the assembly of radial spoke 1 and the motility of mouse cilia and flagella. Cell Rep. 2022 Nov 22;41(8):111683
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory