Iqub^em3Mngx
Endonuclease-mediated Allele Detail

Summary

• Symbol: Iqub^em3Mngx
• Name: IQ motif and ubiquitin domain containing; endonuclease-mediated mutation 3, Mingxi Liu
• MGI ID: MGI:7413080
• Synonyms: Iqub^deltaIQ
• Gene: Iqub Location: Chr6:24444864-24515066 bp, - strand Genetic Position: Chr6, 11.28 cM
• Alliance: Iqub^em3Mngx page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Not Applicable)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 7 removed the IQ motif. (J:332237)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Iqub Mutation: 45 strains or lines available

References

• Original: J:332237 Zhang X, et al., Differential requirements of IQUB for the assembly of radial spoke 1 and the motility of mouse cilia and flagella. Cell Rep. 2022 Nov 22;41(8):111683
• All: 1 reference(s)