Nufip1^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Nufip1^em1Cya
• Name: nuclear FMR1 interacting protein 1; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7413115
• Synonyms: Nufip1^em1(flox)Cya, NUFIP1^fl
• Gene: Nufip1 Location: Chr14:76348337-76372527 bp, + strand Genetic Position: Chr14, 40.35 cM, cytoband D2
• Alliance: Nufip1^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting generated a conditional allele. (J:330821)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nufip1 Mutation: 34 strains or lines available

References

• Original: J:330821 Yuan M, et al., Cancer-associated fibroblasts employ NUFIP1-dependent autophagy to secrete nucleosides and support pancreatic tumor growth. Nat Cancer. 2022 Aug;3(8):945-960
• All: 1 reference(s)