S100a4^em1(cre)Zhyg
Endonuclease-mediated Allele Detail

Summary

• Symbol: S100a4^em1(cre)Zhyg
• Name: S100 calcium binding protein A4; endonuclease-mediated mutation 1, Ying Zhao
• MGI ID: MGI:7413867
• Synonyms: FSP1-CRE, FSP-Cre
• Gene: S100a4 Location: Chr3:90511077-90513349 bp, + strand Genetic Position: Chr3, 39.27 cM, cytoband F1-F2
• Alliance: S100a4^em1(cre)Zhyg page

Mutation origin

• Strain of Origin: FVB/N

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• S100a4^em1(cre)Zhyg expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	S100a4 (MGI:1330282)

• Mutation details: The promoter drives fibroblast-specific expression of the cre recombinase gene. One line was generated. (J:330821)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	S100a4 (mouse) Summary of all recombinase alleles driven by S100a4. Alliance mouse S100a4 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any S100a4 Mutation: 25 strains or lines available

References

• Original: J:330821 Yuan M, et al., Cancer-associated fibroblasts employ NUFIP1-dependent autophagy to secrete nucleosides and support pancreatic tumor growth. Nat Cancer. 2022 Aug;3(8):945-960
• All: 1 reference(s)