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C4bptm1Raw
Targeted Allele Detail
Summary
Symbol: C4bptm1Raw
Name: complement component 4 binding protein; targeted mutation 1, Rick A Wetsel
MGI ID: MGI:7414030
Gene: C4bp  Location: Chr1:130562510-130589365 bp, - strand  Genetic Position: Chr1, 56.89 cM
Alliance: C4bptm1Raw page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:332283
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThe targeting construct replaced the exons encoding Zp3r, C4bp, and Rbms2 with a neomycin resistance cassette. (J:332283)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any C4bp Mutation:  36 strains or lines available
Notes
ES cells = EZ-1 (129)
References
Original:  J:332283 Nonaka MI, et al., Epididymal C4b-binding protein is processed and degraded during transit through the duct and is not essential for fertility. Immunobiology. 2015 Apr;220(4):467-75
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory