Epcam^em3Guoj
Endonuclease-mediated Allele Detail

Summary

• Symbol: Epcam^em3Guoj
• Name: epithelial cell adhesion molecule; endonuclease-mediated mutation 3, Jiao Guo
• MGI ID: MGI:7414387
• Synonyms: -1+9
• Gene: Epcam Location: Chr17:87943407-87958555 bp, + strand Genetic Position: Chr17, 57.87 cM
• Alliance: Epcam^em3Guoj page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• CRISPR-cas9 mediated recombination created a 1 bp deletion and 9 bp insertion (TCCAGTACA) in exon 2. (J:282241)

Expression

In Mice Carrying this Mutation:

503 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Epcam Mutation: 33 strains or lines available

References

• Original: J:282241 Yang Y, et al., Circular RNA profile in liver tissue of EpCAM knockout mice. Int J Mol Med. 2019 Sep;44(3):1063-1077
• All: 3 reference(s)