Hand2os1^em2Shx
Endonuclease-mediated Allele Detail

Summary

• Symbol: Hand2os1^em2Shx
• Name: Hand2, opposite strand 1; endonuclease-mediated mutation 2, Xiaohua Shen
• MGI ID: MGI:7424834
• Gene: Hand2os1 Location: Chr8:57757296-57773894 bp, - strand Genetic Position: Chr8, Syntenic
• Alliance: Hand2os1^em2Shx page

Mutation origin

• Strain of Origin: (C57BL/6J x CBA/Ca2J)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting deleted the 17,098 bp encompassing the full lncRNA while leaving the promoter region intact. (J:330639)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hand2os1 Mutation: 0 strains or lines available

References

• Original: J:330639 Han X, et al., Mouse knockout models reveal largely dispensable but context-dependent functions of lncRNAs during development. J Mol Cell Biol. 2018 Apr 1;10(2):175-178
• All: 1 reference(s)