Dcp2^em1Ysa
Endonuclease-mediated Allele Detail

Summary

• Symbol: Dcp2^em1Ysa
• Name: decapping mRNA 2; endonuclease-mediated mutation 1, Yumiko Saga
• MGI ID: MGI:7425337
• Gene: Dcp2 Location: Chr18:44513569-44558036 bp, + strand Genetic Position: Chr18, 23.74 cM, cytoband B3
• Alliance: Dcp2^em1Ysa page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exon 2. (J:329565)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dcp2 Mutation: 39 strains or lines available

References

• Original: J:329565 Kim J, et al., The RNA helicase DDX6 controls early mouse embryogenesis by repressing aberrant inhibition of BMP signaling through miRNA-mediated gene silencing. PLoS Genet. 2022 Oct;18(10):e1009967
• All: 1 reference(s)