Cyc1^em1(IMPC)Bay
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cyc1^em1(IMPC)Bay
• Name: cytochrome c-1; endonuclease-mediated mutation 1, Baylor College of Medicine
• MGI ID: MGI:7425624
• Synonyms: Cyc1^-
• Gene: Cyc1 Location: Chr15:76227723-76230460 bp, + strand Genetic Position: Chr15, 35.74 cM
• Alliance: Cyc1^em1(IMPC)Bay page
• IMPC: Cyc1 gene page

Cyc1^em1(IMPC)Bay/Cyc1^em1(IMPC)Bay mice exhibit embryonic lethality, with embryos recovered at E7.5 but not at E9.5. Embryos are smaller, show severe developmental delay, forming an epithelium with no obvious embryonic-extraembryonic boundary and abnormal epiblast.

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BL/6N
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cyc1 Mutation: 17 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 3 reference(s)