Ndufa11^em1(IMPC)Bay
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ndufa11^em1(IMPC)Bay
• Name: NADH:ubiquinone oxidoreductase subunit A11; endonuclease-mediated mutation 1, Baylor College of Medicine
• MGI ID: MGI:7425854
• Synonyms: Ndufa11^-
• Gene: Ndufa11 Location: Chr17:57024767-57029141 bp, + strand Genetic Position: Chr17, 29.47 cM, cytoband D
• Alliance: Ndufa11^em1(IMPC)Bay page
• IMPC: Ndufa11 gene page

Ndufa11^em1(IMPC)Bay/Ndufa11^em1(IMPC)Bay mice exhibit embryonic lethality, with embryos recovered at E7.5 but not at E9.5. Embryos are smaller and form a rudimentary egg cylinder but no primitive streak or hallmarks of gastrulation are seen at E7.5.

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BL/6N
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ndufa11 Mutation: 17 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 4 reference(s)