Rps27^em1(IMPC)Bay
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rps27^em1(IMPC)Bay
• Name: ribosomal protein S27; endonuclease-mediated mutation 1, Baylor College of Medicine
• MGI ID: MGI:7425952
• Synonyms: Rps27^-
• Gene: Rps27 Location: Chr3:90119974-90120955 bp, - strand Genetic Position: Chr3, 39.21 cM
• Alliance: Rps27^em1(IMPC)Bay page
• IMPC: Rps27 gene page

Rps27^em1(IMPC)Bay/Rps27^em1(IMPC)Bay mice exhibit embryonic lethality, with embryos recovered at E7.5 but not at E9.5. Embryos are severely developmentally delayed as small egg cylinders with poorly organized extraembryonic tissues and failure of gastrulation.

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BL/6N
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rps27 Mutation: 6 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 4 reference(s)