Prss54^tm1Zgwg
Targeted Allele Detail

Summary

• Symbol: Prss54^tm1Zgwg
• Name: serine protease 54; targeted mutation 1, Zhugang Wang
• MGI ID: MGI:7427434
• Gene: Prss54 Location: Chr8:96285694-96302965 bp, - strand Genetic Position: Chr8, 47.12 cM, cytoband C5
• Alliance: Prss54^tm1Zgwg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:332475
• Parent Cell Line: JM8A3 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The targeting construct replaced exons 4 and 5 with a neomycin resistance cassette. (J:332475)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prss54 Mutation: 20 strains or lines available

References

• Original: J:332475 Shen C, et al., Testis-specific serine protease PRSS54 regulates acrosomal granule localization and sperm head morphogenesis in mice. Biol Reprod. 2022 Oct 11;107(4):1139-1154
• All: 1 reference(s)