About   Help   FAQ
Ccl27aem1Nax
Endonuclease-mediated Allele Detail
Summary
Symbol: Ccl27aem1Nax
Name: C-C motif chemokine ligand 27A; endonuclease-mediated mutation 1, Na Xiong
MGI ID: MGI:7427638
Gene: Ccl27a  Location: Chr4:41769467-41774247 bp, - strand  Genetic Position: Chr4, 22.08 cM
Alliance: Ccl27aem1Nax page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCRISPR/Cas9 technology generated a 126 bp insertion and a 3 bp deletion. This allele was generated in conjunction with Ccl27alem1Nax and Ccl27bem1Nax targeting exon II shared by all three Ccl27 genes. (J:330550)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ccl27a Mutation:  13 strains or lines available
References
Original:  J:330550 Davila ML, et al., CCL27 is a crucial regulator of immune homeostasis of the skin and mucosal tissues. iScience. 2022 Jun 17;25(6):104426
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
06/12/2024
MGI 6.13
The Jackson Laboratory