Ccl27a^em1Nax
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ccl27a^em1Nax
• Name: C-C motif chemokine ligand 27A; endonuclease-mediated mutation 1, Na Xiong
• MGI ID: MGI:7427638
• Gene: Ccl27a Location: Chr4:41769467-41774247 bp, - strand Genetic Position: Chr4, 22.08 cM
• Alliance: Ccl27a^em1Nax page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: CRISPR/Cas9 technology generated a 126 bp insertion and a 3 bp deletion. This allele was generated in conjunction with Ccl27al^em1Nax and Ccl27b^em1Nax targeting exon II shared by all three Ccl27 genes. (J:330550)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ccl27a Mutation: 13 strains or lines available

References

• Original: J:330550 Davila ML, et al., CCL27 is a crucial regulator of immune homeostasis of the skin and mucosal tissues. iScience. 2022 Jun 17;25(6):104426
• All: 1 reference(s)