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Ccl27bem1Nax
Endonuclease-mediated Allele Detail
Summary
Symbol: Ccl27bem1Nax
Name: C-C motif chemokine ligand 27b; endonuclease-mediated mutation 1, Na Xiong
MGI ID: MGI:7427640
Gene: Ccl27b  Location: Chr4:42655251-42655998 bp, + strand  Genetic Position: Chr4, 22.73 cM
Alliance: Ccl27bem1Nax page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsCRISPR/Cas9 technology generated a 4524 bp deletion in exon II. This allele was generated in conjunction with Ccl27aem1Nax and Ccl27alem1Nax targeting exon II shared by all three Ccl27 genes. (J:330550)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ccl27b Mutation:  0 strains or lines available
References
Original:  J:330550 Davila ML, et al., CCL27 is a crucial regulator of immune homeostasis of the skin and mucosal tissues. iScience. 2022 Jun 17;25(6):104426
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory