Defb19^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Defb19^em1Cya
• Name: defensin beta 19; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7427681
• Gene: Defb19 Location: Chr2:152418006-152422232 bp, - strand Genetic Position: Chr2, 75.31 cM
• Alliance: Defb19^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exon 1 and 2. (J:332576)

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Defb19 Mutation: 10 strains or lines available

References

• Original: J:332576 Li X, et al., beta-Defensin 19/119 mediates sperm chemotaxis and is associated with idiopathic infertility. Cell Rep Med. 2022 Dec 20;3(12):100825
• All: 1 reference(s)