Cfap20dc^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cfap20dc^em1(IMPC)J
• Name: CFAP20 domain containing; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:7430786
• Gene: Cfap20dc Location: Chr14:13803533-14038581 bp, + strand Genetic Position: Chr14, 4.87 cM, cytoband A1
• Alliance: Cfap20dc^em1(IMPC)J page
• IMPC: Cfap20dc gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GTACAAACATTAATTGCAAG and AATTTCACCAGTGCCCCAAG, which resulted in a 442 bp deletion beginning at Chromosome 14 position 8,644,284 bp and ending after 8,644,725 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000305379 (exon 4) and 369 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 68 and early truncation 4 amino acids later. (J:188991)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Cfap20dc Mutation: 32 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 2 reference(s)