Zmynd8^em1Lwb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Zmynd8^em1Lwb
• Name: zinc finger, MYND-type containing 8; endonuclease-mediated mutation 1, Weibo Luo
• MGI ID: MGI:7431277
• Synonyms: Zmynd8^fl
• Gene: Zmynd8 Location: Chr2:165626072-165740896 bp, - strand Genetic Position: Chr2, 85.98 cM, cytoband H3
• Alliance: Zmynd8^em1Lwb page

Mutation origin

• Strain of Origin: (C57BL/6 x CBA)F1

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting generated a floxed allele. (J:326848)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zmynd8 Mutation: 504 strains or lines available

References

• Original: J:326848 Luo M, et al., ZMYND8 is a master regulator of 27-hydroxycholesterol that promotes tumorigenicity of breast cancer stem cells. Sci Adv. 2022 Jul 15;8(28):eabn5295
• All: 1 reference(s)