Elfn1^{tm2.1(cre/ERT2)Kama}
Targeted Allele Detail

Summary

• Symbol: Elfn1^{tm2.1(cre/ERT2)Kama}
• Name: leucine rich repeat and fibronectin type III, extracellular 1; targeted mutation 2.1, Kirill Martemyanov
• MGI ID: MGI:7433062
• Synonyms: Elfn1^CreERT2
• Gene: Elfn1 Location: Chr5:139893698-139960477 bp, + strand Genetic Position: Chr5, 78.81 cM
• Alliance: Elfn1^{tm2.1(cre/ERT2)Kama} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:332184
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Elfn1^{tm2.1(cre/ERT2)Kama} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Elfn1 (MGI:2442479)

• Homologous recombination replaced the exon 2 of Elfn1 gene with CreERT2 cassette. (J:332184)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Elfn1 (mouse) Summary of all recombinase alleles driven by Elfn1. Comparative matrix view of recombinase activities Alliance mouse Elfn1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Elfn1 Mutation: 32 strains or lines available

References

• Original: J:332184 Cao Y, et al., Post-developmental plasticity of the primary rod pathway allows restoration of visually guided behaviors. Curr Biol. 2022 Nov 21;32(22):4783-4796.e3
• All: 1 reference(s)