Tg(Fpr-rs3-cre,-GFP)2Irod
Transgene Detail

Summary

• Symbol: Tg(Fpr-rs3-cre,-GFP)2Irod
• Name: transgene insertion 2, Ivan Rodriguez
• MGI ID: MGI:7434275
• Synonyms: Tg(Fpr-rs3-itCre-iGFP)2
• Transgene: Tg(Fpr-rs3-cre,-GFP)2Irod Location: unknown
• Alliance: Tg(Fpr-rs3-cre,-GFP)2Irod page

Transgene origin

• Strain of Origin: (C57BL/6J x DBA/2J)F2

Transgene description

• Transgene Type: Transgenic (Recombinase, Reporter)
• Mutation: Insertion
• Tg(Fpr-rs3-cre,-GFP)2Irod expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Fpr-rs3 (MGI:1278318)

• Mutation details: The BAC RP23-80N19, comprising the entire Fpr-rs3 gene, in which the cassette IRES-Cre-IRES-GFP-frt-Zeo-Puro-Frt was inserted after Fpr-rs3 stop codon. The resistance cassette was removed by in vitro flippase-induced recombination, and the resulting vector was injected into the pronuclei of C57BL6/J-DBA/2J F2 zygotes. Two independent lines were analyzed in this work, labeled as #2 and #4. (J:331962)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Fpr-rs3 (mouse) Summary of all recombinase alleles driven by Fpr-rs3. Comparative matrix view of recombinase activities Alliance mouse Fpr-rs3 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:331962 Dietschi Q, et al., Clustering of vomeronasal receptor genes is required for transcriptional stability but not for choice. Sci Adv. 2022 Nov 18;8(46):eabn7450
• All: 1 reference(s)