Rr357^tm1.1Jta
Targeted Allele Detail

Summary

• Symbol: Rr357^tm1.1Jta
• Name: regulatory region 357; targeted mutation 1.1, Jussi Taipale
• MGI ID: MGI:7434635
• Synonyms: Myc-540^-
• Gene: Rr357 Location: Chr15:61317175-61317176 bp Genetic Position: Chr15, Syntenic
• Alliance: Rr357^tm1.1Jta page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:257088
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Modified regulatory region)
• Mutations: Insertion, Intergenic deletion
• Mutation details: LoxP sites were inserted upstream and downstream of the Myc enhancer. The enhancer was deleted through subsequent cre-mediated recombination, leaving a single loxP site at chr15:61317175 (GRCm39). (J:257088)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rr357 Mutation: 0 strains or lines available

References

• Original: J:257088 Dave K, et al., Mice deficient of Myc super-enhancer region reveal differential control mechanism between normal and pathological growth. Elife. 2017 Jun 6;6:e23382
• All: 1 reference(s)