Col2a1^em2(dre)Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Col2a1^em2(dre)Smoc
• Name: collagen, type II, alpha 1; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
• MGI ID: MGI:7434956
• Synonyms: Col2^dre
• Gene: Col2a1 Location: Chr15:97873483-97902525 bp, - strand Genetic Position: Chr15, 53.97 cM
• Alliance: Col2a1^em2(dre)Smoc page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Col2a1^em2(dre)Smoc expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Col2a1 (MGI:88452)

• The allele was generated by inserting the dre sequence into the endogenous Col2a1 gene locus. (J:333183)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Col2a1 (mouse) Summary of all recombinase alleles driven by Col2a1. Comparative matrix view of recombinase activities Alliance mouse Col2a1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Col2a1 Mutation: 68 strains or lines available

References

• Original: J:333183 Shu HS, et al., Tracing the skeletal progenitor transition during postnatal bone formation. Cell Stem Cell. 2021 Dec 2;28(12):2122-2136.e3
• All: 1 reference(s)