Calhm1^{em1(cre)Marun}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Calhm1^{em1(cre)Marun}
• Name: calcium homeostasis modulator 1; endonuclease-mediated mutation 1, Yoshinori Marunaka
• MGI ID: MGI:7435048
• Synonyms: Calhm1^V5-ires-Cre
• Gene: Calhm1 Location: Chr19:47129474-47132613 bp, - strand Genetic Position: Chr19, 39.36 cM
• Alliance: Calhm1^{em1(cre)Marun} page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Epitope tag, Recombinase)
• Mutation: Insertion
• Calhm1^{em1(cre)Marun} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Calhm1 (MGI:3643383)

• Mutation details: Using CRISPR/Cas9 genome editing, V5 epitope tag-stop codonIRESNLS-Crepoly(A) sequence was inserted immediately before the stop codon in the Calhm1 locus on chromosome 19. (J:333223)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Calhm1 (mouse) Summary of all recombinase alleles driven by Calhm1. Comparative matrix view of recombinase activities Alliance mouse Calhm1 gene page

Expression

In Mice Carrying this Mutation:

10 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Calhm1 Mutation: 13 strains or lines available

References

• Original: J:333223 Taruno A, et al., Post-translational palmitoylation controls the voltage gating and lipid raft association of the CALHM1 channel. J Physiol. 2017 Sep 15;595(18):6121-6145
• All: 2 reference(s)