Elovl5^em1(IMPC)Tcp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Elovl5^em1(IMPC)Tcp
• Name: ELOVL fatty acid elongase 5; endonuclease-mediated mutation 1, The Centre for Phenogenomics
• MGI ID: MGI:7435542
• Gene: Elovl5 Location: Chr9:77824647-77891801 bp, + strand Genetic Position: Chr9, 43.36 cM
• Alliance: Elovl5^em1(IMPC)Tcp page
• IMPC: Elovl5 gene page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of GCTGTCCCTGGACGGCAGCG targeting the 5' side and CCCTACTGTCCTCATTACGA targeting the 3' side of a critical region (ENSMUSE00000218959). This resulted in a 655-bp deletion of Chr9:77883939 to 77884593 (GRCm39). (J:265051)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Elovl5 Mutation: 94 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 2 reference(s)