Tg(Hand1-EGFP/cre)#Abfi
Transgene Detail

Summary

• Symbol: Tg(Hand1-EGFP/cre)#Abfi
• Name: transgene insertion, Anthony B Firulli
• MGI ID: MGI:7435716
• Synonyms: Hand1^LV-Cre
• Transgene: Tg(Hand1-EGFP/cre)#Abfi Location: unknown
• Alliance: Tg(Hand1-EGFP/cre)#Abfi page

Transgene origin

• Strain of Origin: C3HeB/FeJ

Transgene description

• Transgene Type: Transgenic (Recombinase, Reporter)
• Mutation: Insertion
• Tg(Hand1-EGFP/cre)#Abfi expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Hand1 (MGI:103577)

• Mutation details: A transgene consists of a modified eGFP-Cre sequence driven by a 744bp Hand1 LV-specific enhancer and ~2.7Kb Hand1 endogenous promoter specifically within the left ventricle (LV). Two lines were generated with similar expression patterns. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:244253)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Hand1 (mouse) Summary of all recombinase alleles driven by Hand1. Comparative matrix view of recombinase activities Alliance mouse Hand1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:244253 Vincentz JW, et al., Hand factor ablation causes defective left ventricular chamber development and compromised adult cardiac function. PLoS Genet. 2017 Jul;13(7):e1006922
• All: 1 reference(s)