Lyz1^{tm1.1(cre/ERT2)Ngao}
Targeted Allele Detail

Summary

• Symbol: Lyz1^{tm1.1(cre/ERT2)Ngao}
• Name: lysozyme 1; targeted mutation 1.1, Nan Gao
• MGI ID: MGI:7439048
• Synonyms: Lyz^CreER
• Gene: Lyz1 Location: Chr10:117123702-117128773 bp, - strand Genetic Position: Chr10, 65.35 cM
• Alliance: Lyz1^{tm1.1(cre/ERT2)Ngao} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:271577
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Inducible, Recombinase, Reporter)
• Mutation: Insertion
• Lyz1^{tm1.1(cre/ERT2)Ngao} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Lyz1 (MGI:96902)

• Mutation details: A H2BmCherry-IRES-CreER cassette was inserted at start codon ATG of endogenous Lyz1 by homologous recombination in mouse embryonic stem cells. (J:271577)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Lyz1 (mouse) Summary of all recombinase alleles driven by Lyz1. Comparative matrix view of recombinase activities Alliance mouse Lyz1 gene page

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lyz1 Mutation: 15 strains or lines available

References

• Original: J:271577 Yu S, et al., Paneth Cell Multipotency Induced by Notch Activation following Injury. Cell Stem Cell. 2018 Jul 5;23(1):46-59.e5
• All: 3 reference(s)