Rr381^em2Kap
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rr381^em2Kap
• Name: regulatory region 381; endonuclease-mediated mutation 2, Dietmar J Kappes
• MGI ID: MGI:7439127
• Synonyms: Sil^POS
• Gene: Rr381 Location: Chr3:89303454-89303824 bp Genetic Position: Chr3, Syntenic
• Alliance: Rr381^em2Kap page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Modified regulatory region)
• Mutations: Insertion, Intragenic deletion
• Mutation details: In cells containing Zbtb7b silencer deletion allele (Rr381^em1Kap an ssODN template, coding for the orthologous silencer from opossum (Monodelphis domestica), was used with TALEN technology, effectively resulting in the replacement of the endogenous silencer with the marsupial version. (J:333471)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rr381 Mutation: 0 strains or lines available

References

• Original: J:333471 Mookerjee-Basu J, et al., Functional Conservation of a Developmental Switch in Mammals since the Jurassic Age. Mol Biol Evol. 2019 Jan 1;36(1):39-53
• All: 1 reference(s)