Rr381^em3Kap
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rr381^em3Kap
• Name: regulatory region 381; endonuclease-mediated mutation 3, Dietmar J Kappes
• MGI ID: MGI:7439137
• Synonyms: Sil^Flip, ThPOK-SilFlip, ThPOK^SilFlip
• Gene: Rr381 Location: unknown Genetic Position: Chr3, Syntenic
• Alliance: Rr381^em3Kap page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Modified regulatory region)
• Mutation: Other
• Mutation details: The Zbtb7b silencer was targeted with an ssODN template, coding for the silencer sequence in reverse orientation, using TALEN technology (ZNF target sequences (capitalized) ACCGCTACCCTAACCcataaCTGGAAGGGGTTTAG), resulting in its orientation flipping. (J:333471)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rr381 Mutation: 0 strains or lines available

References

• Original: J:333471 Mookerjee-Basu J, et al., Functional Conservation of a Developmental Switch in Mammals since the Jurassic Age. Mol Biol Evol. 2019 Jan 1;36(1):39-53
• All: 1 reference(s)