Guf1^tm1.1Nju
Targeted Allele Detail

Summary

• Symbol: Guf1^tm1.1Nju
• Name: GUF1 homolog, GTPase; targeted mutation 1.1, Model Animal Research Center of Nanjing University
• MGI ID: MGI:7439318
• Gene: Guf1 Location: Chr5:69714255-69731995 bp, + strand Genetic Position: Chr5, 37.13 cM
• Alliance: Guf1^tm1.1Nju page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:333298
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct floxed exons 2 through 8. Cre-mediated recombination removed exons 2 through 8. (J:333298)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Guf1 Mutation: 43 strains or lines available

References

• Original: J:333298 Gao Y, et al., Mammalian elongation factor 4 regulates mitochondrial translation essential for spermatogenesis. Nat Struct Mol Biol. 2016 May;23(5):441-9
• All: 1 reference(s)