Tg(Crhr1-icre,-tdTomato)3Njus
Transgene Detail

Summary

• Symbol: Tg(Crhr1-icre,-tdTomato)3Njus
• Name: transgene insertion 3, Nicholas J Justice
• MGI ID: MGI:7439324
• Synonyms: Crfr1-cre
• Transgene: Tg(Crhr1-icre,-tdTomato)3Njus Location: unknown
• Alliance: Tg(Crhr1-icre,-tdTomato)3Njus page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Recombinase, Reporter)
• Mutation: Insertion
• Tg(Crhr1-icre,-tdTomato)3Njus expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Crhr1 (MGI:88498)

• Mutation details: A BAC (rp23-239f10) containing the entire genomic locus of mouse Crhr1 was modified using recombineering. A cassette encoding iCre-p2A-tdTomato-PA was inserted in the first exon at the site of the ATG start codon for the Crhr1 gene. Three independent transgenic lines were recovered. The line 3 was established and used for analyses. (J:257545)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Crhr1 (mouse) Summary of all recombinase alleles driven by Crhr1. Comparative matrix view of recombinase activities Alliance mouse Crhr1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:257545 Jiang Z, et al., Local Corticotropin-Releasing Factor Signaling in the Hypothalamic Paraventricular Nucleus. J Neurosci. 2018 Feb 21;38(8):1874-1890
• All: 1 reference(s)