Tg(Bhlhe41-icre,-CD2)#Mbu
Transgene Detail

Summary

• Symbol: Tg(Bhlhe41-icre,-CD2)#Mbu
• Name: transgene insertion, Meinrad Busslinger
• MGI ID: MGI:7439462
• Synonyms: Bhlhe41-Cre-hCD2
• Transgene: Tg(Bhlhe41-icre,-CD2)#Mbu Location: unknown
• Alliance: Tg(Bhlhe41-icre,-CD2)#Mbu page

Transgene origin

• Strain of Origin: (C57BL/6 CBA)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence, Recombinase)
• Mutation: Insertion
• Tg(Bhlhe41-icre,-CD2)#Mbu expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Bhlhe41 (MGI:1930704)

• Mutation details: BAC RP23-343I17 was used to create a transgene in which the expression of icre was under the control of the Bhlhe41 promoter by inserting icre linked by an IRES to a truncated human CD2 sequence into the Bhlhe41 locus. (J:258170)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Bhlhe41 (mouse) Summary of all recombinase alleles driven by Bhlhe41. Alliance mouse Bhlhe41 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:258170 Kreslavsky T, et al., Essential role for the transcription factor Bhlhe41 in regulating the development, self-renewal and BCR repertoire of B-1a cells. Nat Immunol. 2017 Apr;18(4):442-455
• All: 1 reference(s)