Tg(Pdzk1ip1-cre/ERT2)#Reiz
Transgene Detail

Summary

• Symbol: Tg(Pdzk1ip1-cre/ERT2)#Reiz
• Name: transgene insertion, Boris Reizis
• MGI ID: MGI:7439529
• Synonyms: Pdzk1ip1-CreER
• Transgene: Tg(Pdzk1ip1-cre/ERT2)#Reiz Location: unknown
• Alliance: Tg(Pdzk1ip1-cre/ERT2)#Reiz page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Pdzk1ip1-cre/ERT2)#Reiz expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Pdzk1ip1 (MGI:1914432)

• Mutation details: The fusion of Cre recombinase and optimized estrogen receptor ligand-binding domain (CreERT2) was inserted into the first Pdzk1ip1 exon in the RP23-68O6 BAC clone. Three founder lines were generated. One line in pure C57BL/6 background was chosen for all further experimentation. The line number was not provided. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:259030)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Pdzk1ip1 (mouse) Summary of all recombinase alleles driven by Pdzk1ip1. Comparative matrix view of recombinase activities Alliance mouse Pdzk1ip1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:259030 Sawai CM, et al., Hematopoietic Stem Cells Are the Major Source of Multilineage Hematopoiesis in Adult Animals. Immunity. 2016 Sep 20;45(3):597-609
• All: 4 reference(s)