Fer1l6^tm1Osb
Targeted Allele Detail

Summary

• Symbol: Fer1l6^tm1Osb
• Name: fer-1 like family member 6; targeted mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:7440012
• Synonyms: Fer1l6^{tm1a(KOMP)Osb}
• Gene: Fer1l6 Location: Chr15:58381897-58536936 bp, + strand Genetic Position: Chr15, 24.88 cM
• Alliance: Fer1l6^tm1Osb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:333204
• Parent Cell Line: EGR-G01 (ES Cell)
• Strain of Origin: (129S2/SvPas x C57BL/6NSlc)F1-Tg(CAG-EGFP,Acr-EGFP)2Osb

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting construct obtained from IMPC inserted downstream of exon 3 a loxP site, lacZ reporter gene, FRT site, neomycin resistance cassette, loxP site, and FRT site. An additional loxP site was inserted downstream of exon 4. (J:333204)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fer1l6 Mutation: 89 strains or lines available

References

• Original: J:333204 Morohoshi A, et al., Testis-enriched ferlin, FER1L5, is required for Ca(2+)-activated acrosome reaction and male fertility. Sci Adv. 2023 Jan 25;9(4):eade7607
• All: 1 reference(s)