Tg(Gata3*-cre)2481Jeng
Transgene Detail

Summary

• Symbol: Tg(Gata3*-cre)2481Jeng
• Name: transgene insertion 2481, James Douglas Engel
• MGI ID: MGI:7442302
• Synonyms: Tg^coreOVE-Cre, Tg^{OVE core-Cre}
• Transgene: Tg(Gata3*-cre)2481Jeng Location: unknown
• Alliance: Tg(Gata3*-cre)2481Jeng page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA)F1

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Gata3*-cre)2481Jeng expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Gata3 (MGI:95663)

• Mutation details: A 1.3-kb DNA fragment bearing the (300-bp) Gata3 promoter plus 1 kb of the first intron was linked to the 3' 246-bp sequence from the otic vesicle enhancer (OVE) referred to as the core OVE in the Gata3 locus in BAC clone 260A19 drives cre expression to the inner ear specifically. One line 2481 was established. (J:267996)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Gata3 (mouse) Summary of all recombinase alleles driven by Gata3. Comparative matrix view of recombinase activities Alliance mouse Gata3 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:267996 Moriguchi T, et al., A Gata3 3' Distal Otic Vesicle Enhancer Directs Inner Ear-Specific Gata3 Expression. Mol Cell Biol. 2018 Nov 1;38(21)
• All: 1 reference(s)