Tg(Ins1-cre/ERT2)#Pesch
Transgene Detail

Summary

• Symbol: Tg(Ins1-cre/ERT2)#Pesch
• Name: transgene insertion, Philipp E Scherer
• MGI ID: MGI:7442903
• Synonyms: MIP-CreER^T2
• Transgene: Tg(Ins1-cre/ERT2)#Pesch Location: unknown
• Alliance: Tg(Ins1-cre/ERT2)#Pesch page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Ins1-cre/ERT2)#Pesch expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Ins1 (MGI:96572)

• Mutation details: The 1983-bp CreERT2 coding sequence is driven by an 8.3-kb mouse insulin 1 promoter. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:268878)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Ins1 (mouse) Summary of all recombinase alleles driven by Ins1. Comparative matrix view of recombinase activities Alliance mouse Ins1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:268878 Ye R, et al., Autonomous interconversion between adult pancreatic alpha-cells and beta-cells after differential metabolic challenges. Mol Metab. 2016 Jul;5(7):437-448
• All: 1 reference(s)