Tg(Pdpn-cre)HRkl
Transgene Detail

Summary

• Symbol: Tg(Pdpn-cre)HRkl
• Name: transgene insertion, Raghu Kalluri
• MGI ID: MGI:7442946
• Synonyms: PDPN-Cre, Tg(PDPN-cre)#Rkl
• Transgene: Tg(Pdpn-cre)HRkl Location: unknown
• Alliance: Tg(Pdpn-cre)HRkl page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Pdpn-cre)HRkl expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Pdpn (MGI:103098)

• A 4-kb mouse Pdpn promoter sequence ligated to a Cre recombinase sequence. Founder line H was used. (J:269567)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Pdpn (mouse) Summary of all recombinase alleles driven by Pdpn. Comparative matrix view of recombinase activities Alliance mouse Pdpn gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:269567 Chen Y, et al., Podoplanin+ tumor lymphatics are rate limiting for breast cancer metastasis. PLoS Biol. 2018 Dec;16(12):e2005907
• All: 1 reference(s)