Rr395em1Bhao
Endonuclease-mediated Allele Detail
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Symbol: |
Rr395em1Bhao |
Name: |
regulatory region 395; endonuclease-mediated mutation 1, Bingtao Hao |
MGI ID: |
MGI:7444372 |
Synonyms: |
Ets2-SE- |
Gene: |
Rr395 Location: Chr16:95546632-95713561 bp Genetic Position: Chr16, Syntenic
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Alliance: |
Rr395em1Bhao page
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Strain of Origin: |
Not Applicable
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Allele Type: |
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Endonuclease-mediated (Modified regulatory region, Null/knockout) |
Mutations: |
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Intergenic deletion, Intragenic deletion
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Rr395em1Bhao involves 7 genes/genome features (Gm6599, Gm37259, Gm32130 ...)
View all
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Mutation details: The Ets2 super-enhancer, located downstream of the gene, was targeted using CRISPR/Cas9 technology, resulting in a 166.930 kb deletion (chr16:95546632-95713561 (GRCm39)). The deletion contains numerous predicted enhancers plus (part of) the 1600002D24Rik, 2810404F17Rik, and Gm15340 (predicted) lncRNA genes.
(J:333961)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Rr395 Mutation: |
0 strains or lines available
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Original: |
J:333961 Feng D, et al., Chromatin organizer SATB1 controls the cell identity of CD4(+) CD8(+) double-positive thymocytes by regulating the activity of super-enhancers. Nat Commun. 2022 Sep 22;13(1):5554 |
All: |
1 reference(s) |
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