Pla2g4e^em1Murm
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pla2g4e^em1Murm
• Name: phospholipase A2, group IVE; endonuclease-mediated mutation 1, Makoto Murakami
• MGI ID: MGI:7444531
• Gene: Pla2g4e Location: Chr2:119996893-120075816 bp, - strand Genetic Position: Chr2, 60.24 cM
• Alliance: Pla2g4e^em1Murm page

Mutation origin

• Strain of Origin: C57BL/6NSlc

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 13 deleted 13 bp. (J:333700)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pla2g4e Mutation: 53 strains or lines available

References

• Original: J:333700 Liang L, et al., Group IVE cytosolic phospholipase A2 limits psoriatic inflammation by mobilizing the anti-inflammatory lipid N-acylethanolamine. FASEB J. 2022 May;36(5):e22301
• All: 2 reference(s)