Hadh^em1Jgao
Endonuclease-mediated Allele Detail

Summary

• Symbol: Hadh^em1Jgao
• Name: hydroxyacyl-Coenzyme A dehydrogenase; endonuclease-mediated mutation 1, Jiangang Gao
• MGI ID: MGI:7444796
• Gene: Hadh Location: Chr3:131027068-131065750 bp, - strand Genetic Position: Chr3, 60.86 cM
• Alliance: Hadh^em1Jgao page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exons 2 through 6. (J:333351)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hadh Mutation: 19 strains or lines available

References

• Original: J:333351 Zhu H, et al., Hadh deficiency induced oligoasthenoteratozoospermia through the TNF-alpha/Bcl-2 pathway in male mice. FASEB J. 2022 Dec;36(12):e22661
• All: 1 reference(s)