Slc17a7^{tm1.1(cre)Ahan}
Targeted Allele Detail

Summary

• Symbol: Slc17a7^{tm1.1(cre)Ahan}
• Name: solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7; targeted mutation 1.1, Adam W Hantman
• MGI ID: MGI:7446770
• Synonyms: Slc17a7-IRES-Cre
• Gene: Slc17a7 Location: Chr7:44813373-44825566 bp, + strand Genetic Position: Chr7, 29.16 cM
• Alliance: Slc17a7^{tm1.1(cre)Ahan} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:314932
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Slc17a7^{tm1.1(cre)Ahan} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Slc17a7 (MGI:1920211)

• Mutation details: The targeting vector inserted an IRES-Cre cassette into the 3-untranslated region immediately downstream of exon 12 of the Slc17a7 gene. The positive selection cassette was removed by breeding F1 progeny with a codon-optimized FLP recombinase (FLPo) germline deleter strain. (J:314932)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Slc17a7 (mouse) Summary of all recombinase alleles driven by Slc17a7. Comparative matrix view of recombinase activities Alliance mouse Slc17a7 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc17a7 Mutation: 40 strains or lines available

References

• Original: J:314932 Huang CC, et al., Convergence of pontine and proprioceptive streams onto multimodal cerebellar granule cells. Elife. 2013 Feb 26;2:e00400
• All: 3 reference(s)