Lyve1^{em3(cre/ERT2)Gpt}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Lyve1^{em3(cre/ERT2)Gpt}
• Name: lymphatic vessel endothelial hyaluronan receptor 1; endonuclease-mediated mutation 3, GemPharmatech Co., Ltd
• MGI ID: MGI:7446935
• Synonyms: Lyve1-CreERT2, Lyve1^CreERT2
• Gene: Lyve1 Location: Chr7:110449814-110462160 bp, - strand Genetic Position: Chr7, 57.89 cM, cytoband F2
• Alliance: Lyve1^{em3(cre/ERT2)Gpt} page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Lyve1^{em3(cre/ERT2)Gpt} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Lyve1 (MGI:2136348)

• CRISPR-targeting inserted cre/ERT2 into the Lyve1 locus. (J:330324)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Lyve1 (mouse) Summary of all recombinase alleles driven by Lyve1. Comparative matrix view of recombinase activities Alliance mouse Lyve1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lyve1 Mutation: 15 strains or lines available

References

• Original: J:330324 Masuda T, et al., Specification of CNS macrophage subsets occurs postnatally in defined niches. Nature. 2022 Apr;604(7907):740-748
• All: 1 reference(s)