Kdm2b^{em1(cre/ERT2)Bcgen}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Kdm2b^{em1(cre/ERT2)Bcgen}
• Name: lysine (K)-specific demethylase 2B; endonuclease-mediated mutation 1, Biocytogen LLC
• MGI ID: MGI:7449219
• Synonyms: Kdm2b^CreERT2
• Gene: Kdm2b Location: Chr5:123008727-123127333 bp, - strand Genetic Position: Chr5, 62.63 cM, cytoband F
• Alliance: Kdm2b^{em1(cre/ERT2)Bcgen} page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Inducible, Recombinase, Reporter)
• Inducer: tamoxifen
• Mutation: Insertion
• Kdm2b^{em1(cre/ERT2)Bcgen} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Kdm2b (MGI:1354737)

• Mutation details: CRISPR/cas9 mediated recombination introduced a sequence encoding the self-cleaving T2A peptide was fused in frame with exon 3 of the Kdm2b followed by the CreERT2-IRES-EGFP cassette. (J:297829)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Kdm2b (mouse) Summary of all recombinase alleles driven by Kdm2b. Comparative matrix view of recombinase activities Alliance mouse Kdm2b gene page

Expression

In Mice Carrying this Mutation:

26 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kdm2b Mutation: 220 strains or lines available

References

• Original: J:297829 Li W, et al., Long non-coding RNA LncKdm2b regulates cortical neuronal differentiation by cis-activating Kdm2b. Protein Cell. 2020 Mar;11(3):161-186
• All: 1 reference(s)