Krt4^{em1(cre/ERT2)Bcgen}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Krt4^{em1(cre/ERT2)Bcgen}
• Name: keratin 4; endonuclease-mediated mutation 1, Biocytogen LLC
• MGI ID: MGI:7449308
• Synonyms: Ck4^CreERT2
• Gene: Krt4 Location: Chr15:101826970-101833170 bp, - strand Genetic Position: Chr15, 57.13 cM
• Alliance: Krt4^{em1(cre/ERT2)Bcgen} page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Krt4^{em1(cre/ERT2)Bcgen} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Krt4 (MGI:96701)

• The CreERT2 cassette is under the control of the Krt4 promoter. (J:305876)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Krt4 (mouse) Summary of all recombinase alleles driven by Krt4. Comparative matrix view of recombinase activities Alliance mouse Krt4 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Krt4 Mutation: 19 strains or lines available

References

• Original: J:305876 Guo W, et al., Single-cell transcriptomics identifies a distinct luminal progenitor cell type in distal prostate invagination tips. Nat Genet. 2020 Sep;52(9):908-918
• All: 1 reference(s)