Adad2^em1Shnk
Endonuclease-mediated Allele Detail

Summary

• Symbol: Adad2^em1Shnk
• Name: adenosine deaminase domain containing 2; endonuclease-mediated mutation 1, Satoshi H Namekawa
• MGI ID: MGI:7450907
• Synonyms: Adad2^Mut1
• Gene: Adad2 Location: Chr8:120339486-120343663 bp, + strand Genetic Position: Chr8, 68.05 cM, cytoband E1
• Alliance: Adad2^em1Shnk page
• IMPC: Adad2 gene page

Mutation origin

• Strain of Origin: C57BL/6
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 2 deleted 47 bp. (J:334463)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adad2 Mutation: 19 strains or lines available

References

• Original: J:334463 Xiong M, et al., ADAD2 interacts with RNF17 in P-bodies to repress the Ping-pong cycle in pachytene piRNA biogenesis. J Cell Biol. 2023;222(5):e202206067
• All: 1 reference(s)