Samd1^tm1Pfi
Targeted Allele Detail

Summary

• Symbol: Samd1^tm1Pfi
• Name: sterile alpha motif domain containing 1; targeted mutation 1, Pfizer, Ltd
• MGI ID: MGI:7451188
• Gene: Samd1 Location: Chr8:84724145-84727044 bp, + strand Genetic Position: Chr8, 40.24 cM
• Alliance: Samd1^tm1Pfi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:333561
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The targetign construct replaced most of exon 1 through exon 5 with a neomycin resistance cassette. (J:333561)

Expression

In Mice Carrying this Mutation:	29 assay results
In Structures Affected by this Mutation:	11 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Samd1 Mutation: 8 strains or lines available

References

• Original: J:333561 Campbell B, et al., Investigation of SAMD1 ablation in mice. Sci Rep. 2023 Feb 21;13(1):3000
• All: 1 reference(s)