Tg(Sox3-cre/ERT2)#Syos
Transgene Detail

Summary

• Symbol: Tg(Sox3-cre/ERT2)#Syos
• Name: transgene insertion, Shosei Yoshida
• MGI ID: MGI:7461181
• Synonyms: Sox3-CreER^T2
• Transgene: Tg(Sox3-cre/ERT2)#Syos Location: unknown
• Alliance: Tg(Sox3-cre/ERT2)#Syos page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Sox3-cre/ERT2)#Syos expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Sox3 (MGI:98365)

• Mutation details: The transgene was constructed by using a BAC clone (RP23-150I6) containing the entire Sox3 gene, which is a single-exon gene, plus 211 kb flanking sequence by replacing the entire coding sequence of Sox3 with the CreERT2 sequence. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:328290)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Sox3 (mouse) Summary of all recombinase alleles driven by Sox3. Comparative matrix view of recombinase activities Alliance mouse Sox3 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:328290 Nakagawa T, et al., A multistate stem cell dynamics maintains homeostasis in mouse spermatogenesis. Cell Rep. 2021 Oct 19;37(3):109875
• All: 1 reference(s)