Mir124a-2^tm1.1Tfur
Targeted Allele Detail

Summary

• Symbol: Mir124a-2^tm1.1Tfur
• Name: microRNA 124a-2; targeted mutation 1.1, Takahisa Furukawa
• MGI ID: MGI:7461659
• Gene: Mir124a-2 Location: Chr3:17849826-17849934 bp, + strand Genetic Position: Chr3, 4.98 cM
• Alliance: Mir124a-2^tm1.1Tfur page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:333877
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct replaced the sequence with a floxed neomycin resistance cassette. Cre-mediated recombination removed the selection cassette. (J:333877)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mir124a-2 Mutation: 3 strains or lines available

References

• Original: J:333877 Chaya T, et al., Multiple knockout mouse and embryonic stem cell models reveal the role of miR-124a in neuronal maturation. J Biol Chem. 2022 Jul 20;298(9):102293
• All: 1 reference(s)