Atl1^tm1.2Cbla
Targeted Allele Detail

Summary

• Symbol: Atl1^tm1.2Cbla
• Name: atlastin GTPase 1; targeted mutation 1.2, Craig Blackstone
• MGI ID: MGI:7463986
• Synonyms: Atl1^-
• Gene: Atl1 Location: Chr12:69939879-70010859 bp, + strand Genetic Position: Chr12, 28.94 cM
• Alliance: Atl1^tm1.2Cbla page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:334532
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre-mediated recombination of the floxed Atl1^tm1.1Cbla allele deleted exon 3 generating a knock-out allele. (J:334532)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atl1 Mutation: 29 strains or lines available

References

• Original: J:334532 Zhu PP, et al., Transverse endoplasmic reticulum expansion in hereditary spastic paraplegia corticospinal axons. Hum Mol Genet. 2022 Aug 23;31(16):2779-2795
• All: 1 reference(s)