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Krt6aem1(icre)Vk
Endonuclease-mediated Allele Detail
Summary
Symbol: Krt6aem1(icre)Vk
Name: keratin 6A; endonuclease-mediated mutation 1, Vesa Kaartinen
MGI ID: MGI:7464182
Synonyms: Krt6aiCre
Gene: Krt6a  Location: Chr15:101598363-101602746 bp, - strand  Genetic Position: Chr15, 56.97 cM
Alliance: Krt6aem1(icre)Vk page
Mutation
origin
Strain of Origin:  C57BL/6 x SJL
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Krt6aem1(icre)Vk expression driven by 1 gene
 
Mutation detailsCRISPR/Cas9 genome editing is used to introduce the iCre-pA cassettes at the Krt6a initiator methionine site in exon 1. (J:325729, J:334621)
Recombinase
activity
Activity:
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Driver: Krt6a (mouse)
Summary of all recombinase alleles driven by Krt6a.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Krt6a Mutation:  25 strains or lines available
References
Original:  J:334621 Saroya G, et al., Periderm Fate during Palatogenesis: TGF-beta and Periderm Dedifferentiation. J Dent Res. 2023 Apr;102(4):459-466
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory