Tg(Nmur1-icre,-EGFP)1Dart
Transgene Detail

Summary

• Symbol: Tg(Nmur1-icre,-EGFP)1Dart
• Name: transgene insertion 1, David Artis
• MGI ID: MGI:7464238
• Synonyms: Nmur1^iCre-eGFP, Tg(Nmur1-iCre,-eGFP)1Dart
• Transgene: Tg(Nmur1-icre,-EGFP)1Dart Location: unknown
• Alliance: Tg(Nmur1-icre,-EGFP)1Dart page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Recombinase, Reporter)
• Mutation: Insertion
• Tg(Nmur1-icre,-EGFP)1Dart expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Nmur1 (MGI:1341898)

• Mutation details: The transgene was generated by replacing exons 2 and 3 of neuromedin U receptor 1 (Nmur1 gene), in the mouse BAC RP23-403I3, with a P2A-iCre-T2A-EGFP cassette followed by an FRT-flanked Kanamycin cassette. The FRT flanked kanamycin cassette was removed by FLP-mediated recombination. The modified BAC construct was microinjected into the pronucleus of C57BL/6 zygotes and randomly integrated into the mouse genome. Founder line 1 was established and then subsequently maintained (J:334817)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Nmur1 (mouse) Summary of all recombinase alleles driven by Nmur1. Comparative matrix view of recombinase activities Alliance mouse Nmur1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:334817 Tsou AM, et al., Neuropeptide regulation of non-redundant ILC2 responses at barrier surfaces. Nature. 2022 Nov;611(7937):787-793
• All: 4 reference(s)